Patent · US Active

Mutated DNA polymerases with increased mispairing discrimination

US8759061B1 · kind B1 · utility

16Cited by

0References

27Claims

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Assignee

Rheinische Friedrich-Wilhems-Universitaet Bonn · DE

Inventors

Andreas Marx · Reilingen, DE
Daniel Summerer · Konstanz, DE
Nicolas Rudinger · Goldkronach, DE

Key dates

Filing date	Feb 4, 2005
Grant date	Jun 24, 2014
Priority date	—
Expiry date	Nov 16, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6858
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to DNA polymerases with a special mutation which have an enhanced mismatch discrimination, the preparation and use thereof. The thermostable DNA polymerases with this mutation are particularly suitable for diagnostic and molecular-biological methods, e.g., allele-specific PCR.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.