Temperature control device with a flexible temperature control surface

US8759085B2 · kind B2 · utility

Assignee

• Akonni Biosystems, Inc. · US

Inventors

• Phil Belgrader · Severna Park, US
• Christopher G. Cooney · Severn, US
• Robert Doebler · Upland, US
• Anna Hickerson · Altadena, US
• Bruce Irvine · Burns Lake, CA
• Ali Nadim · San Marino, US
• James D. Sterling · Upland, US
• Reza Miraghaie · Culver City, US

Key dates

• Filing date: Apr 29, 2011
• Grant date: Jun 24, 2014
• Expiry date: Mar 6, 2033

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2300/185
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.