Maintenance of platelet inhibition during antiplatelet therapy

US8759316B2 · kind B2 · utility

Assignee

• THE MEDICINES COMPANY · US

Inventors

• Lisa Ruderman Chen · Rye, US
• Simona Skerjanec · Basel, CH
• Dawn Bell · Morristown, US
• Jayne Prats · Carlisle, US
• Meredith Todd · Hoboken, US
• Clive Arthur Arculus-Meanwell · Bernardsville, US
• Diane R. Mould · Fort Myers, US

Key dates

• Filing date: Jun 28, 2013
• Grant date: Jun 24, 2014
• Expiry date: Jun 28, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/7076
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for reducing or maintaining platelet inhibition in a patient by administering cangrelor prior to an invasive procedure is described. The method of this invention can be used for patients in need of antiplatelet therapy or at risk of thrombosis. The method can further be used in patients who were previously treated with long-acting platelet inhibitors without increasing the risk of excessive bleeding.