Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections
US8759318B2 · kind B2 · utility
55Cited by
8References
78Claims
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Key dates
| Filing date | Jan 11, 2010 |
| Grant date | Jun 24, 2014 |
| Priority date | — |
| Expiry date | Sep 9, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/167
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Phosphoramidate compounds derived from guanine bases having enhanced therapeutic potency are provided, and these compounds in particular have enhanced potency with respect to treatment of viral infections, such as hepatitis C virus. Pharmaceutical compositions, methods of preparing the compounds, and methods of using the compounds and compositions to treat viral infections are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.