Compounds and methods for controlling fungi

US8759356B2 · kind B2 · utility

Assignee

• DOW AGROSCIENCES LLC · US

Inventors

• Francis E. Tisdell · Carmel, US
• James M. Renga · Midland, US
• William C. Lo · Fishers, US
• Maurice C. Yap · Zionsville, US
• David H. Young · Ambler, US
• George E. Davis · Carmel, US

Key dates

• Filing date: May 3, 2010
• Grant date: Jun 24, 2014
• Expiry date: Sep 28, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Various aspects disclosed herein relate to aryl substituted aminopyrimidines according to Formula 1:wherein, X1 is N or C—R3; X2 is N or C—R4 provided that X1 and X2 are not both N; R1-R7 are H, CN, CHO, —SCN, NO2, F, Cl, Br, I, substituted or unsubstituted C1-C4-alkyl, substituted or unsubstituted halo-C1-C4-alkyl, substituted or unsubstituted C1-C4-alkoxy, substituted or unsubstituted halo-C1-C4-alkoxy, substituted or unsubstituted C1-C4-thioalkyl, substituted or unsubstituted halo-C1-C4-thioalkyl, substituted or unsubstituted C3-C-7-cycloalkyl, substituted or unsubstituted C2-C4-alkenyl, C2-C4-alkynyl, substituted or unsubstituted C1-C4-acylalkyl, C1-C4-acyloxy, C1-C4 alkoxycarbonyl, C1-C4-alkoxy-amino, C1-C4-alkyl-S(O)═NH, substituted or unsubstituted aryl, substituted or unsubstituted heterocycle, wherein the substituents are one or more of the following F, Cl, Br, OH, CN, NO2, CHO, —SCN, S(O)n-C1-C4-alkyl (where n=0-2), C1-C4-alkyl, halo-C1-C4-alkyl, C1-C4-alkylamine, C1-C4-alkoxy, halo-C1-C4-alkoxy, C1-C4-thioalkyl, halo-C1-C4-thioalkyl, C1-C4-alkylacyl, C1-C4-acyloxy, C1-C4 alkoxycarbonyl, C1-C4-alkoxy-imino, hydroxy-imino; C1-C4-alkyl-S(O)═NH; and Q is a substituted or uns…