Two-photon absorbing water soluble fluorescent probe as a near-neutral pH indicator
US8759381B1 · kind B1 · utility
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1References
6Claims
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Assignee
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Key dates
| Filing date | Jul 11, 2012 |
| Grant date | Jun 24, 2014 |
| Priority date | — |
| Expiry date | Jul 11, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC09K2211/1037
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are fluorescent compounds useful as intracellular pH probes. In particular, the invention teaches a two-photon absorbing, water soluble, fluorescent compound, a fluorene derivative, which is effective as a near-neutral pH indicator and particularly as an intracellular probe. A method for chemical synthesis of the claimed compounds is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.