Patent · US Active

Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds

US8759388B2 · kind B2 · utility

38Cited by
24References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 9, 2012
Grant dateJun 24, 2014
Priority date
Expiry dateApr 9, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, and diseases characterized by abnormal growth, such as cancers. The invention further provides compositions containing the beta or gamma-amino isoquinoline amide compounds or substituted benzamide compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.