Oligosaccharides comprising an aminooxy group and conjugates thereof
US8759501B2 · kind B2 · utility
8Cited by
39References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 18, 2008 |
| Grant date | Jun 24, 2014 |
| Priority date | — |
| Expiry date | Nov 4, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01076
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.