Patent · US Active

Mono-hydrochloric salts of an inhibitor of histone deacetylase

US8759519B2 · kind B2 · utility

0Cited by

1References

4Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Julius Walter Jozef Dickens · Beerse, BE
Ioannes Nicolaos Houpis · Ekeren, BE
Yolande Lydia Lang · Vosselaar, BE
Carina Leys · Stabroek, BE
Sigrid Carl Maria Stokbroekx · Beerse, BE
Johan Erwin Edmond Weerts · Beerse, BE

Key dates

Filing date	May 30, 2012
Grant date	Jun 24, 2014
Priority date	—
Expiry date	Jun 25, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention provides novel crystalline forms of mono-HCl salts and a mono-HCl salt hydrate of JNJ-26481585, an inhibitor of histone deacetylases. The invention also relates to processes for production of these forms, to intermediates used in these processes, to pharmaceutical compositions comprising these forms, and to the use of these forms in medical treatment for instance as a medicine to inhibit proliferative conditions, such as cancer and leukemia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.