Method for preparing optionally substituted p-hydroxymandelic compounds and derivatives thereof
US8759573B2 · kind B2 · utility
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4References
23Claims
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Key dates
| Filing date | Dec 9, 2008 |
| Grant date | Jun 24, 2014 |
| Priority date | — |
| Expiry date | Oct 7, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/367
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a method for preparing optionally substituted P-hydroxymandelic compounds and derivatives thereof. The method for preparing the mandelic compounds of the invention comprises condensing in water, in the presence of an alkaline agent, an aromatic compound bearing at least one hydroxyl group and having a free para position, with glycoxylic acid, wherein said method is characterised in that said reaction is carried out in a piston-flow reactor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.