Methods of predicting cancer risk using gene expression in premalignant tissue
US8765383B2 · kind B2 · utility
7Cited by
0References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 2010 |
| Grant date | Jul 1, 2014 |
| Priority date | — |
| Expiry date | Mar 8, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides methods for assessing a patient's cancer risk and/or recurrence risk, which methods comprise assaying, in a biological sample obtained from the gastrointestinal (GI) tract of the patient, an expression level of a risk gene. The present disclosure also provides methods involving a cancer risk/recurrence risk sequence, i.e. the V600E mutation of the BRAF gene, which is useful for assessing cancer risk and/or recurrence risk in a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.