Chimeric adenoviruses for use in cancer treatment
US8765463B2 · kind B2 · utility
9Cited by
10References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2012 |
| Grant date | Jul 1, 2014 |
| Priority date | — |
| Expiry date | Apr 10, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10344
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.