Solifenacin salts

US8765785B2 · kind B2 · utility

Assignee

• CRYSTAL PHARMA, S.A.U. · ES

Inventors

• Gerardo Gutiérrez Fuentes · Boecillo, ES
• Antonio Lorente Bonde-Larsen · Valladolid, ES
• Jaime del Campo López-Bachiller · Boecillo, ES
• Celso Sandoval Rodríguez · Boecillo, ES
• Yolanda Fernández Sainz · Valladolid, ES

Key dates

• Filing date: Jul 5, 2011
• Grant date: Jul 1, 2014
• Expiry date: Jul 5, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/439
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns fumarate salts of solifenacin, as well as pharmaceutical compositions comprising fumarate salts of solifenacin. The invention furthermore concerns a process for preparing solifenacin and salts thereof. The fumarate salt provides improved properties over the known solifenacin salts, especially in terms of its stability. The novel process for its preparation is furthermore improved over known processes for preparing solifenacin in that it provides a higher yield and recovers a greater amount of starting material.