Patent · US Active

Peptide derivatives with therapeutic activity

US8765798B2 · kind B2 · utility

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0References

3Claims

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Assignee

FLAMMA SPA · IT

Inventors

Gianpaolo Negrisoli · Chignolo d'Isola, IT
Renato Canevotti · Vimercate, IT

Key dates

Filing date	Jun 15, 2007
Grant date	Jul 1, 2014
Priority date	—
Expiry date	May 20, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Dipeptide compounds containing a histidine residue proved to have interesting blocking activity on secondary products from lipid oxidative stress, in particular on unsaturated aldehydes such as malondialdehyde and hydroxynonenal, which are known to contribute to the inset of quite a number of chronic pathologies such as neurodegenerative, inflammatory chronic, cardiovascular diseases, diabetes complications and cataract.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.