Advanced methods and systems for treating cell proliferation disorders
US8770203B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 14, 2009 |
| Grant date | Jul 8, 2014 |
| Priority date | — |
| Expiry date | May 5, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/7052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods for treating cell proliferation disorders comprising (1) administering to the subject at least one activatable pharmaceutical agent that is capable of activation by a simultaneous two photon absorption event and of effecting a predetermined cellular change when activated, (2) administering at least one plasmonics-active agent to the subject, and (3) applying an initiation energy from an initiation energy source to the subject, wherein the plasmonics-active agent enhances or modifies the applied initiation energy, such that the enhanced or modified initiation energy activates the activatable pharmaceutical agent by the simultaneous two photon absorption event in situ, thus causing the predetermined cellular change to occur, wherein said predetermined cellular change treats the cell proliferation related disorder, and the use of plasmonics enhanced photospectral therapy (PEPST) and exiton-plasmon enhanced phototherapy (EPEP) in the treatment of various cell proliferation disorders, and the PEPST and EPEP agents and probes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.