Ex vivo methods for testing toxicity of substances using donated human organs or tissues
US8771930B2 · kind B2 · utility
8Cited by
21References
23Claims
0Family size
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Key dates
| Filing date | May 18, 2007 |
| Grant date | Jul 8, 2014 |
| Priority date | — |
| Expiry date | Jun 12, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06Q20/102
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Properties such as toxicity of substances may be determined by assaying properties, fates and effects of substances in an ex vivo metabolically active human organ or tissue under normothermic perfusion with a fluid containing a test substance. The data can be used as, for example, part of a submission to a government regulatory organization. Preferred methods use perfused endocrine gland organs or tissues to evaluate hormone or other bodily chemical disruption caused by substances and pre-donation diseased or injured organs or tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.