Enzymatic synthesis of sulfated polysaccharides
US8771995B2 · kind B2 · utility
7Cited by
5References
6Claims
0Family size
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Key dates
| Filing date | Mar 12, 2012 |
| Grant date | Jul 8, 2014 |
| Priority date | — |
| Expiry date | Mar 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P19/64
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Heparin is synthesized from a polysaccharide comprised of a 1-4 glycosidically linked alternating polymer of uronic acid and glucosamine residues, wherein the uronic acid is selected from iduronic and glucuronic acid, wherein the glucosamine is partially N-sulfated; by a series of selective reactions catalyzed by recombinant enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.