Patent · US Active

Promoters for recombinant viral expression

US8772023B2 · kind B2 · utility

0Cited by

0References

24Claims

0Family size

Assignee

Bavarian Nordic A/S · DK

Inventors

Robin Steigerwald · Munich, DE
Christine Meisinger-Henschel · Schwanau, DE
Eva Felder · Munich, DE

Key dates

Filing date	Nov 27, 2009
Grant date	Jul 8, 2014
Priority date	—
Expiry date	Dec 27, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2840/60
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a promoter selected from a group of nucleic acids consisting of (a) a nucleic acid having the nucleotide sequence of SEQ ID NO:1; (b) a nucleic acid having a nucleotide sequence derived from SEQ ID NO:1, wherein not more than 10 nucleotides have been added, deleted, substituted and/or inverted from the nucleic acid of SEQ ID NO:1; and (c) a nucleic acid sequence having at least 70% identity with the nucleic acid of (a); wherein the promoter has a length of up to and including 27 nucleotides and wherein the promoter according to options (b) and (c) exhibits at least the 70% of the promoter activity of SEQ ID NO:1 as measured by the amount of recombinant protein produced.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.