Method of administration of gamma hydroxybutyrate with monocarboxylate transporters
US8772306B1 · kind B1 · utility
70Cited by
28References
34Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 29, 2013 |
| Grant date | Jul 8, 2014 |
| Priority date | — |
| Expiry date | Apr 29, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H20/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
One embodiment of the present invention is to improve the safety and efficacy of the administration of GHB or a salt thereof to a patient. It has been discovered that the concomitant administration of an MCT inhibitor, such as diclofenac, valproate, or ibuprofen, will affect GHB administration. For example, it has been discovered that diclofenac lowers the effect of GHB in the body, thereby potentially causing an unsafe condition. Furthermore, it has been discovered that valproate increases the effect of GHB on the body, thereby potentially causing an unsafe condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.