Patent · US Active

Aptamer regulated nucleic acids and uses thereof

US8772464B2 · kind B2 · utility

1Cited by

56References

18Claims

0Family size

Assignee

CALIFORNIA INSTITUTE OF TECHNOLOGY · US

Inventors

Christina D. Smolke · Menlo Park, US
Travis S. Bayer · San Francisco, US

Key dates

Filing date	Feb 9, 2006
Grant date	Jul 8, 2014
Priority date	—
Expiry date	Apr 24, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to aptamer-regulated, ligand-responsive nucleic acids, or “ampliSwitches,” and uses thereof. Particular embodiments include a ligand-responsive nucleic acid that comprises a primer sequence domain and an aptamer domain that is responsive to a ligand.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.