Inhibitors of PI3 kinase and/or mTOR

US8772480B2 · kind B2 · utility

Assignee

• AMGEN INC. · US

Inventors

• Kristin L. Andrews · Thousand Oaks, US
• Yunxin Y. Bo · Thousand Oaks, US
• Shon Booker · Thousand Oaks, US
• Victor J. Cee · Thousand Oaks, US
• Noel D'Angelo · Thousand Oaks, US
• Bradley J. Herberich · Newbury Park, US
• Fang-Tsao Hong · Thousand Oaks, US
• Claire L. M. Jackson · Thousand Oaks, US
• Brian Alan LANMAN · Calabasas, US
• Hongyu Liao · Thousand Oaks, US
• Longbin Liu · Thousand Oaks, US
• Nobuko Nishimura · Calabasas, US
• Mark H. Norman · Thousand Oaks, US
• Liping H. Pettus · Thousand Oaks, US
• Anthony B. Reed · Newbury Park, US
• Adrian L. Smith · Simi Valley, US
• Seifu Tadesse · Simi Valley, US
• Nuria A. Tamayo · Newbury Park, US
• Bin Wu · Thousand Oaks, US
• Ryan Wurz · Newbury Park, US
• Kevin Yang · San Gabriel, US

Key dates

• Filing date: Nov 19, 2012
• Grant date: Jul 8, 2014
• Expiry date: Nov 19, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereof;methods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds, wherein the variables are as defined herein.