Method and device for identification of nucleated red blood cells from a maternal blood sample
US8774488B2 · kind B2 · utility
8Cited by
204References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 11, 2011 |
| Grant date | Jul 8, 2014 |
| Priority date | — |
| Expiry date | Mar 11, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N5/0087
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for concentrating and isolating nucleated cells, such as a maternal and fetal nucleated red blood cells (NRBC's), in a maternal whole blood sample. The invention also provides methods and apparatus for preparing to analyze and analyzing the sample for identification of fetal genetic material as part of prenatal genetic testing. The invention also pertains to methods and apparatus for discriminating fetal nucleated red blood cells from maternal nucleated red blood cells obtained from a blood sample taken from a pregnant woman.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.