Method of forming an injectable radioactive composition of a carbon encapsulated radioactive particulate

US8778300B2 · kind B2 · utility

Assignee

• The Australian National University · AU

Inventors

• Rodney James Browitt · North Canberra, AU
• William M. Burch · Sydney, AU
• Timothy John Senden · North Canberra, AU
• Ross Stephens · North Canberra, AU

Key dates

• Filing date: Apr 28, 2006
• Grant date: Jul 15, 2014
• Expiry date: Apr 18, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K51/1244
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of forming an injectable radioactive composition, the method comprising the steps of: (a) depositing a solid form of technetium onto a carbon crucible; (b) preheating the solid form of technetium to remove any carrier; (c) plasma ablating the technetium and portions of the carbon crucible; (d) allowing the carbon and technetium metal to co-condense from the gas phase to produce a nanoparticle composite aerosol in an inert gas; (e) dispersing the nanoparticle composite in water containing a low concentration of surfactant using an electrostatic precipitator; (f) size fractionating the nanoparticle dispersion by filtration with hydrophilic membranes of known pore size.