Vaccines comprising heat-sensitive transgenes
US8778683B2 · kind B2 · utility
2Cited by
0References
13Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 7, 2010 |
| Grant date | Jul 15, 2014 |
| Priority date | — |
| Expiry date | Oct 7, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/572
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides temperature sensitive essential nucleic acid molecules from a psychrophilic bacterium, proteins encoded by the nucleic acid molecules, as well as recombinant cells into which have been introduced such nucleic acid molecules. The disclosed recombinant cells containing one or more essential nucleic acid molecules from a psychrophilic bacterium are thereby made temperature sensitive, and can be administered to a mammal to induce an immune response in the mammal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.