Patterned flow-cells useful for nucleic acid analysis
US8778848B2 · kind B2 · utility
52Cited by
85References
34Claims
0Family size
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Key dates
| Filing date | Jun 8, 2012 |
| Grant date | Jul 15, 2014 |
| Priority date | — |
| Expiry date | Aug 24, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/447
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided is a surface having metal regions and an interstitial region having a composition that differs from the metal regions, wherein a continuous gel layer coats the surface across the metal regions and the interstitial regions. Nucleic acids or other analytes can be attached to the continuous gel layer such that a greater amount is attached over the metal regions than over the interstitial region. Also provided are methods for making such surfaces. Methods are also provided for making an array of nucleic acids or other analytes using such surfaces.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.