Patent · US Active

Modified factor IX polypeptides and uses thereof

US8778870B2 · kind B2 · utility

19Cited by

33References

37Claims

0Family size

Assignee

Catalyst Biosciences, Inc. · US

Inventors

Edwin L. Madison · Dallas, US
Christopher D. Thanos · Tiburon, US
Grant E. BLOUSE · Burlingame, US

Key dates

Filing date	Nov 3, 2011
Grant date	Jul 15, 2014
Priority date	—
Expiry date	Nov 3, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K48/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Modified Factor IX (FIX) polypeptides and uses thereof are provided. Such modified FIX polypeptides include FIXa and other forms of FIX. Among the modified FIX polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.