TRPM8 antagonists and their use in treatments
US8778941B2 · kind B2 · utility
1Cited by
52References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 21, 2012 |
| Grant date | Jul 15, 2014 |
| Priority date | — |
| Expiry date | Jun 21, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure:where the definitions of the variables are provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.