Method for the manufacture of aminohydroxy diphosphonic acids
US8779135B2 · kind B2 · utility
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5References
13Claims
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Assignee
Inventors
Key dates
| Filing date | Oct 4, 2010 |
| Grant date | Jul 15, 2014 |
| Priority date | — |
| Expiry date | Oct 4, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/59
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The technology of this invention concerns a method for the manufacture of hydroxy diphosphonic acids containing an amino moiety. The method specifically involves reacting a liquid P4O6 with an aminocarboxylic acid in the presence of a sulfonic acid. The aminocarboxylic acid is selected from 3 structurally different compounds. The amino hydroxy diphosphonic acids can be synthesized with high selectivity and purity and the unreacted starting raw materials can easily and conveniently be recirculated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.