Substituted 2,3,4,4A,5,9B-hexahydro-1H-pyrido[4,3-B]indole derivatives synthesis and uses thereof

US8779139B2 · kind B2 · utility

Assignee

• INTRA-CELLULAR THERAPIES, INC. · US

Inventors

• John Charles Tomesch · Succasunna, US
• Peng Li · New York, US
• Wei Yao · Shanghai, CN
• Qiang Zhang · Dalian, CN
• James David Beard · New York, US
• Andrew S. Thompson · Mountainside, US
• Hua Cheng · Plainsboro, US
• Lawrence P. Wennogle · Fryeburg, US

Key dates

• Filing date: Aug 23, 2012
• Grant date: Jul 15, 2014
• Expiry date: Aug 23, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides methods for the preparation of substituted 2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole derivative useful as intermediates and methods for producing and using such intermediates.