Cilostazol cocrystals and compositions
US8779146B2 · kind B2 · utility
0Cited by
11References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2011 |
| Grant date | Jul 15, 2014 |
| Priority date | — |
| Expiry date | Apr 28, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/4709
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to improvements of the physiochemical and/or the pharmaceutical properties of cilostazol. Disclosed herein are several new compositions and cocrystals of cilostazol, including: a 1:1 cilostazol gentisic acid cocrystal, a 1:1:1 cilostazol gentisic acid H2O cocrystal, a 1:1 cilostazol 4-hydroxybenzoic acid cocrystal, and a 1:1 cilostazol 2,4-dihydroxybenzoic acid cocrystal. The therapeutic methods and uses of these cilostazol cocrystals are described as well as therapeutic compositions containing them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.