Fluoro-pyridinone derivatives useful as antibacterial agents

US8779148B2 · kind B2 · utility

Assignee

• PFIZER INC. · US

Inventors

• Usa Reilly · West Haven, US
• Michael Joseph Melnick · Portage, US
• Matthew Frank Brown · Stonington, US
• Mark Plummer · Westbrook, US
• Justin Ian Montgomery · Ledyard, US
• Ye Che · Groton, US
• Loren Michael Price · Groton, US

Key dates

• Filing date: Oct 31, 2013
• Grant date: Jul 15, 2014
• Expiry date: Oct 31, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.