Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
US8779175B2 · kind B2 · utility
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57References
50Claims
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Key dates
| Filing date | May 26, 2010 |
| Grant date | Jul 15, 2014 |
| Priority date | — |
| Expiry date | Mar 31, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A coordination complex having a physiologically acceptable pKa includes a metal and a biologically active agent. The pKa of the coordination complex is less than the pKa of the biologically active agent. A pharmaceutical solution for treating a patient includes a coordination complex and water, wherein the coordination complex is at least partially soluble in the water at physiological pH and in a therapeutically efficacious concentration. A method for treating a patient includes administering a pharmaceutical solution including a coordination complex and water to a patient in need of a biologically active agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.