Transdermal administration of tamsulosin
US8784879B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2010 |
| Grant date | Jul 22, 2014 |
| Priority date | — |
| Expiry date | Oct 7, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P13/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In an aspect of the invention, a composition for making a patch for the transdermal delivery of tamsulosin is provided. The composition comprises (a) at least about 1 wt % tamsulosin or a pharmaceutically acceptable salt of tamsulosin, (b) at least about 40 wt % polyisobutylene adhesive or hydrophobic synthetic rubber adhesive, (c) about 1-20 wt % of an aprotic solvent in which tamsulosin dissolves readily, (d) about 1-20 wt % of an unsaturated fatty acid or an alpha-hydroxy acid or a mixture of unsaturated fatty acids or alpha-hydroxy acids or of both unsaturated fatty acids and alpha-hydroxy acids, (e) a lipophilic permeation enhancer, and (f) a matrix modifier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.