Inhibitors of mammalian tight junction opening
US8785374B2 · kind B2 · utility
7Cited by
1References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 20, 2008 |
| Grant date | Jul 22, 2014 |
| Priority date | — |
| Expiry date | Nov 23, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel peptides that inhibit and/or reduce the opening of mammalian tight junctions, i.e. peptide tight junction antagonists. The present invention also provides methods for the treatment of excessive or undesirable permeability of a tissue by administering to a subject suffering from such a condition a composition comprising a peptide tight junction antagonist of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.