Compound and method for treatment of alzheimer's disease and familial dementia
US8785391B2 · kind B2 · utility
3Cited by
2References
13Claims
0Family size
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Inventor
Key dates
| Filing date | Jun 24, 2010 |
| Grant date | Jul 22, 2014 |
| Priority date | — |
| Expiry date | Jun 24, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An isolated protein is provided for use in treatment of a condition selected from the group consisting of Alzheimer's disease, familial Danish dementia and familial British dementia in a mammal, including man. The isolated protein is selected from the group consisting of proteins comprising an amino acid sequence having at least 70% identity to residues 90-236 of Bri2 from human; and proteins comprising an amino acid sequence having at least 70% identity to any one of the Brichos domains of Bri2 from human, chimpanzee, bovine, pig, mouse and rat.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.