Process for preparing bosentan

US8785461B2 · kind B2 · utility

Assignee

• Generics [UK] Limited · GB

Inventors

• Abhay Gaitonde · Jamkhed, IN
• Bindu Manojkumar · Jamkhed, IN
• Sandeep Mekde · Jamkhed, IN
• Vikas Padalkar · Jamkhed, IN
• Hemant Mande · Jamkhed, IN

Key dates

• Filing date: Feb 6, 2009
• Grant date: Jul 22, 2014
• Expiry date: Jun 11, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/69
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a novel intermediate useful in the preparation of bosentan and to processes for the preparation of said intermediate and bosentan. The invention further relates to compositions comprising bosentan prepared according to the processes of the invention and their use in the treatment of endothelin-receptor mediated disorders.