Functional imaging

US8787643B2 · kind B2 · utility

Assignee

• KONINKLIJKE PHILIPS B.V. · NL

Inventors

• Manoj Narayanan · Mentor, US
• Jens-Christoph Georgi · Aachen, DE
• Frank Olaf Thiele · Aachen, DE
• Ralph Brinks · Hagen, DE
• Michael Perkuhn · Eindhoven, NL

Key dates

• Filing date: Jan 12, 2010
• Grant date: Jul 22, 2014
• Expiry date: Dec 23, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30204
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method includes generating a kinetic parameter value for a VOI in a functional image of a subject based on motion corrected projection data using an iterative algorithm, including determining a motion correction for projection data corresponding to the VOI based on the VOI, motion correcting the projection data corresponding to the VOI to generate the motion corrected projection data, and estimating the at least one kinetic parameter value based on the motion corrected projection data or image data generated with the motion corrected projection data. In another embodiment, a method includes registering functional image data indicative of tracer uptake in a scanned patient with image data from a different imaging modality, identifying a VOI in the image based on the registered images, generating at least one kinetic parameter for the VOI, and generating a feature vector including the at least one generated kinetic parameter and at least one bio-marker.