Stable pharmaceutical composition containing docetaxel and a method of manufacturing the same
US8791152B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 2007 |
| Grant date | Jul 29, 2014 |
| Priority date | — |
| Expiry date | Nov 12, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.