Pro-fluorescent probes
US8791258B2 · kind B2 · utility
10Cited by
21References
27Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 8, 2009 |
| Grant date | Jul 29, 2014 |
| Priority date | — |
| Expiry date | Sep 15, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/206664
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a novel class of pro-fluorescent probes for reactive oxygen species (ROS). One exemplary probe is mitochondria peroxy yellow 1 (MitoPY1), a new type of flurophore for imaging mitochondrial H2O2 in living cells with ROS and spatial specificity. The invention also provides methods of using pro-fluorescent probes to detect analytes. One exemplary method comprises using a pro-fluorescent probe of the invention to detect an explosive.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.