Microbial cell and particle selection system and method of use
US8795498B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2013 |
| Grant date | Aug 5, 2014 |
| Priority date | — |
| Expiry date | Oct 17, 2033 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB03C5/005
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention comprises two key components: dielectrophoresis (DEP) and reversible binding surfaces. DEP has become an important tool for trapping dielectric particles. Moreover, DEP can manipulate cell movement as dictated by the intrinsic dielectric constant of the cell without modification. DEP therefore provides a mechanism by which to force targets in a flow channel to a reversible binding surface. By building selectivity into the binding surface, the capacity to choose which targets can be held after the dielectric field is turned off, providing a separation strategy that does not suffer from fouling issues, as large foulants can freely pass over the surface through the flow channel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.