Patent · US Active

Genes encoding major capsid protein L1 of human papilloma virus

US8795676B2 · kind B2 · utility

0Cited by

2References

12Claims

0Family size

Assignee

Shanghai Zerun Biotechnology Co., Ltd. · CN

Inventors

Gaoxia Zhang · Shanghai, CN
Qiong Shen · Shanghai, CN
Jianqiang Lei · Shanghai, CN
Jingyu Yuan · Shanghai, CN
Menghua Zhang · Shanghai, CN
Qianli Zhang · Longbeilingcun, CN
Yinghua Xiong · Shanghai, CN
Roger Wei · Shanghai, CN
Ke Wu · Shanghai, CN

Key dates

Filing date	Nov 24, 2008
Grant date	Aug 5, 2014
Priority date	—
Expiry date	Apr 12, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2982
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention discloses a codon-optimized gene encoding major capsid protein L1 of human papilloma virus, which is capable, after transduced into a yeast cell, of efficiently expressing the major capsid protein L1 of human papilloma virus. The present invention also discloses an immunogenic macromolecule which is essentially produced by expression of said codon-optimized gene encoding the major capsid protein L1 of human papilloma virus in a yeast cell. The present invention further discloses the use of said immunogenic macromolecule and a composition comprising said immunogenic macromolecule.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.