Methods and compositions for diagnosis and risk prediction in heart failure
US8795975B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 25, 2011 |
| Grant date | Aug 5, 2014 |
| Priority date | — |
| Expiry date | Nov 25, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/60
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates in part to diagnosing the occurrence of heart failure, particularly in subjects who exhibit a normal body fluid level of a natriuretic peptide. The present invention further relates in part to assigning an outcome risk (e.g., worsening cardiac function or a mortality risk, a risk of rehospitalization) to a subject. The methods comprise performing one or more assays that detect one or more biomarkers selected from the group consisting of WAP4C, ESAM, LTBR, Mesothelin, and Syndecan-1 performed on a body fluid sample obtained from a subject, and assigning diagnosis or risk based, at least in part, on the result(s) obtained thereby.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.