Patent · US Active

Polypeptides for a ketoreductase-mediated stereoselective route to alpha chloroalcohols

US8796002B2 · kind B2 · utility

0Cited by

10References

22Claims

0Family size

Assignee

Codexis, Inc. · US

Inventors

Yong Koy Bong · Singapore, SG
Michael Vogel · Saterland, DE
Steven J. Collier · Concord, US
Vesna Mitchell · San Jose, US
Jagadeesh Mavinahalli · Jamkhed, IN

Key dates

Filing date	Jun 22, 2010
Grant date	Aug 5, 2014
Priority date	—
Expiry date	Feb 21, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y101/01184
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of α chloroalcohols from α chloroketones. Also provided are polynucleotides encoding the engineered ketoreductase polypeptides and host cells capable of expressing the engineered ketoreductase polypeptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.