Patent · US Active

Label free kinase assays and reagents

US8796003B1 · kind B1 · utility

1Cited by
10References
18Claims
0Family size

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Key dates

Filing dateAug 8, 2012
Grant dateAug 5, 2014
Priority date—
Expiry dateAug 19, 2032

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2500/04
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This disclosure describes methods and compositions for measuring the binding specificity, kinetics and affinity of kinase inhibitors indirectly using mass sensing analytical techniques, such as SPR, through the competitive displacement of detectable signal-inducing kinase binding molecule. Further provided are methods for preparing such molecules.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.