Enzyme treatment of foodstuffs for celiac sprue

US8796201B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Lu Shan · Houston, US
• Michael Bethune · Pasadena, US
• Chaitan Khosla · Palo Alto, US
• Jonathan David Gass · Mountain View, US
• Gail G. Pyle · Cupertino, US
• Gary Gray · Stanford, US
• Indu Isaacs · Andover, US
• Gregg Strohmeier · Newton, US

Key dates

• Filing date: Nov 4, 2011
• Grant date: Aug 5, 2014
• Expiry date: Nov 10, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.