Pyrazolo [1,5-a]-pyrimidones derivatives and pharmaceutical compositions and uses thereof

US8796285B2 · kind B2 · utility

Assignees

• Hebei Medical University · CN
• Peking University · CN

Inventors

• Hailin Zhang · Lo Wu, CN
• Jinlong Qi · Shijiazhuang, CN
• Diqun Zhang · Shijiazhuang, CN
• Kewei Wang · Beijing, CN
• Fan Zhang · Lake Barrington, US
• Yan Fu · Shanghai, CN
• Yi Mi · Shijiazhuang, CN
• Wen Xu · Shanghai, CN
• Xiaona Du · Shijiazhuang, CN
• Yibing Wu · Shijiazhuang, CN
• Qingzhong Jia · Shijiazhuang, CN
• Shuangge Yang · Shijiazhuang, CN

Key dates

• Filing date: Jun 3, 2010
• Grant date: Aug 5, 2014
• Expiry date: Jun 23, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides new pyrazol-[1,5-a]-pyrimidone derivates and pharmaceutical compositions comprising said compounds and one or more pharmaceutically acceptable carriers or diluents. The uses of the compounds for the manufacture of potassium channel openers, anti-epilepsy medicaments, anti-anxiety medicaments and analgesic medicaments are also provided in the present invention.