Substituted fused pyrimidine compounds, its preparation and uses thereof

US8796290B2 · kind B2 · utility

Assignee

• Advinus Therapeutics Limited

Inventors

• Vidya Ramdas · Pune, IN
• Summon Koul · Pimpri-Chinchwad, IN
• Sujay Basu · Mumbai, IN
• Yogesh Waman · Pune, IN
• Yogesh Shejul · Pimpri-Chinchwad, IN
• Dinesh Barawkar · Lake Forest, US
• Venkata P. Palle · Mountain View, US

Key dates

• Filing date: Nov 9, 2010
• Grant date: Aug 5, 2014
• Expiry date: Nov 9, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D473/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides substituted fused pyrimidine compounds of formula (I), their tautomers, polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by adenosine receptor (AR) activity. The present invention also provides processes for preparation of compounds of formula (I).