TRPV1 antagonists

US8796328B2 · kind B2 · utility

Inventors

• Arthur Gomtsyan · Vernon Hills, US
• Jerome F. Daanen · Racine, US
• Michael E. Kort · Lake Bluff, US
• Philip R. Kym · Libertyville, US
• Eric A. Voight · Pleasant Prairie, US
• Kevin R. Woller · Antioch, US

Key dates

• Filing date: Jun 20, 2013
• Grant date: Aug 5, 2014
• Expiry date: Jun 20, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compounds of formula (I) or pharmaceutically acceptable salts, prodrugs, or combinations thereof,wherein X1, L, Rx, Ry, Rz, R1, R2, A, m, n, p, q, and r are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.