Patent · US Active

Human epidermal growth factor receptor variant lacking an exon

US8796421B2 · kind B2 · utility

1Cited by

0References

8Claims

0Family size

Assignee

SHANGHAI CANCER INSTITUTE · CN

Inventors

Zonghai LI · Shanghai, CN
Min Zhou · Suzhou, CN
Hai Wang · San Diego, US
Bizhi Shi · Shanghai, CN
Shengli Yang · 安丰镇, CN
Hongyang Wang · Hefei, CN
Jianren Gu · Shanghai, CN

Key dates

Filing date	Oct 24, 2011
Grant date	Aug 5, 2014
Priority date	—
Expiry date	Oct 24, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/485
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides an epidermal growth factor receptor variant-de4 EGFR protein. The variant lacks the fourth exon of the epidermal growth factor receptor, and promotes tumor cell invasion/metastasis. The present invention also provides an encoding gene for the variant and a method of producing the variant by means of recombination technology.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.