Combined hairpin-antisense compositions and methods for modulating expression
US8796442B2 · kind B2 · utility
0Cited by
6References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 20, 2008 |
| Grant date | Aug 5, 2014 |
| Priority date | — |
| Expiry date | Mar 20, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/53
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A nucleotide construct comprising a nucleotide sequence that forms a stem and a loop, wherein the loop comprises a nucleotide sequence that modulates expression of a target, wherein the stem comprises a nucleotide sequence that modulates expression of a target, and wherein the target modulated by the nucleotide sequence in the loop and the target modulated by the nucleotide sequence in the stem may be the same or different. Vectors, methods of regulating target expression, methods of providing a cell, and methods of treating conditions comprising the nucleotide sequence are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.